Search results for " hospital workers"

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Nucleoplasmic bridges and acrocentric chromosome associations as early markers of exposure to low levels of ionising radiation in occupationally expo…

2014

Ionising radiation, with the contribution of telomere shortening, induces DNA double-strand breaks that result in chromosome end fusion, nucleoplasmic bridges (NPBs) and chromosome aberrations (ChAbs) as well as dicentric chromosomes. In order to investigate the chromosomal damage induced by occupational ionising radiation at low exposure levels, and to find early markers of health hazard, peripheral lymphocytes of occupationally exposed hospital workers were cytogenetically analysed. Results showed a significant difference in the frequency of ChAbs in exposed subjects relative to controls. A significant number of NPBs between nuclei of binucleated cultured lymphocytes from exposed subjects…

AdultHealth Toxicology and MutagenesisLymphocyteBiologyToxicologyIonizing radiationAndrologyDicentric chromosomeOccupational ExposureRadiation IonizingCentromereGeneticsmedicineHumansLymphocytesIn Situ Hybridization FluorescenceGenetics (clinical)Cell NucleusChromosome AberrationsChromosomeEarly cytogenetics markers hospital workersMolecular biologyTelomereChromatinPersonnel HospitalSettore BIO/18 - GeneticaCell nucleusmedicine.anatomical_structureBiomarkersMutagenesis
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